NEUL1_MOUSE Q923S6
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UniProt:Q923S6
Recommended name:E3 ubiquitin-protein ligase NEURL1
EC number:EC 2.3.2.27
Alternative names:(Neuralized-like protein 1A) (m-neu1) (m-neuralized 1) (Neuralized1) (RING-type E3 ubiquitin transferase NEURL1)
Cleaved into:
GeneID:18011
Gene names (primary ):Neurl1
Gene names (synonym ):Neurl Neurl1a
Gene names (ORF ):
Length:574
Mass:61778
Sequence:MGNNFSSVSSLQRGNPSRASRGHPQNLKDSIGGSFPVPSHRCHHKQKHCPPTLSGGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFSGVRTVDPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRCEADEARLSVSLCDLNVPGADGDDGAPPAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARLEHGRDERALVFTSRPVRVAETIFIKVTRSGGGRAGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMTERGGPSLPCSPASTPTSPSALGIRLSDPLLSTCGSGPLGGSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYSCGLRLKKALHACCPICRRPIKDIIKTYRSS
Tissue specificity:Expressed in CA1 pyramidal neurons (at protein level). Expressed throughout the adult forebrain, including the cerebral cortex, amygdala, striatum, and CA1 area of the hippocampus. Expressed in sensory neurons of the olfactory epithelium, the vomeronasal organ, mammary gland and skeletal muscle. {ECO:0000269|PubMed:11481456, ECO:0000269|PubMed:11585928, ECO:0000269|PubMed:22153079}.
Induction:Up-regulated by synaptic activity. {ECO:0000269|PubMed:22153079}.
Developmental stage:Expressed in the somites at 8.5 dpc onwards. {ECO:0000269|PubMed:11481456, ECO:0000269|PubMed:11585928}.
Protein families: