SELW_MOUSE P63300
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UniProt:P63300
Recommended name:Selenoprotein W
EC number:
Alternative names:(SelW)
Cleaved into:
GeneID:20364
Gene names (primary ):Selenow
Gene names (synonym ):Selw Sepw1
Gene names (ORF ):
Length:88
Mass:9687
Sequence:MALAVRVVYCGAUGYKPKYLQLKEKLEHEFPGCLDICGEGTPQVTGFFEVTVAGKLVHSKKRGDGYVDTESKFRKLVTAIKAALAQCQ
Tissue specificity:In the embryo, expressed in the developing nervous system and in mesoderm-derived tissues such as heart and limbs. In the adult, predominantly expressed in brain, skeletal muscle and heart. {ECO:0000269|PubMed:16876868, ECO:0000269|PubMed:17503775}.
Induction:Down-regulated by hydrogen peroxide. Increased levels are detected after treatment with L-buthionine sulfoxide (BSO) before exposure to hydrogen peroxide. {ECO:0000269|PubMed:16876868}.
Developmental stage:Expression is first detected in the newly implanted embryo. Levels increase gradually during embryonic development with a steady increase during the second week and a dramatic increase by the end of gestation. Expression increases gradually in proliferating myotubes but is low in terminally differentiated myobutubes. {ECO:0000269|PubMed:16876868}.
Protein families:SelWTH family, Selenoprotein W subfamily