BCAT1_MOUSE P24288
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UniProt:P24288
Recommended name:Branched-chain-amino-acid aminotransferase, cytosolic
EC number:EC 2.6.1.42
Alternative names:(BCAT(c)) (Protein ECA39)
Cleaved into:
GeneID:12035
Gene names (primary ):Bcat1
Gene names (synonym ):Eca39
Gene names (ORF ):
Length:386
Mass:42791
Sequence:MKDCSNGCSAPFAGERGSEEVAETFRAKDLIITPATVLKEKPDPDSLVFGATFTDHMLTVEWSSASGWEKPHIKPFGNLPIHPAASVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMDRMCRSAVRTTLPMFDKEELLKCILQLLQIDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPSKALLFVILSPVGPYFSSGSFTPVSLWANPKYIRAWKGGTGDCKMGGNYGASLLAQCEAVENGCQQVLWLYGKDNQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRQSILELAQQWGEFKVCERHLTMDDLATALEGNRVKEMFGSGTACVVCPVSDILYKGQMLHIPTMENGPKLASRILGKLTDIQYGRVESDWTIELP
Tissue specificity:Expressed in brain and kidney. Overexpressed in MYC-induced brain tumors, lymphomas, as well as in a teratocarcinoma cell line.
Induction:
Developmental stage:Highly expressed at day 9 of embryogenesis. Expression decreases to moderate levels through day 13. In the developing embryo, expressed in the brain, somites and mesenophric tubules.
Protein families:Class-IV pyridoxal-phosphate-dependent aminotransferase family