BCAT1_MOUSE   P24288


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UniProt:P24288

Recommended name:Branched-chain-amino-acid aminotransferase, cytosolic

EC number:EC 2.6.1.42

Alternative names:(BCAT(c)) (Protein ECA39)

Cleaved into:

GeneID:12035

Gene names  (primary ):Bcat1

Gene names  (synonym ):Eca39

Gene names  (ORF ):

Length:386

Mass:42791

Sequence:MKDCSNGCSAPFAGERGSEEVAETFRAKDLIITPATVLKEKPDPDSLVFGATFTDHMLTVEWSSASGWEKPHIKPFGNLPIHPAASVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMDRMCRSAVRTTLPMFDKEELLKCILQLLQIDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPSKALLFVILSPVGPYFSSGSFTPVSLWANPKYIRAWKGGTGDCKMGGNYGASLLAQCEAVENGCQQVLWLYGKDNQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRQSILELAQQWGEFKVCERHLTMDDLATALEGNRVKEMFGSGTACVVCPVSDILYKGQMLHIPTMENGPKLASRILGKLTDIQYGRVESDWTIELP

Tissue specificity:Expressed in brain and kidney. Overexpressed in MYC-induced brain tumors, lymphomas, as well as in a teratocarcinoma cell line.

Induction:

Developmental stage:Highly expressed at day 9 of embryogenesis. Expression decreases to moderate levels through day 13. In the developing embryo, expressed in the brain, somites and mesenophric tubules.

Protein families:Class-IV pyridoxal-phosphate-dependent aminotransferase family


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