TBX1_MOUSE P70323
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UniProt:P70323
Recommended name:T-box transcription factor TBX1
EC number:
Alternative names:(T-box protein 1) (Testis-specific T-box protein)
Cleaved into:
GeneID:21380
Gene names (primary ):Tbx1
Gene names (synonym ):
Gene names (ORF ):
Length:479
Mass:51668
Sequence:MHFSTVTRDMEAFAASSLSGLGSPSPGADPFGPREPPPPRYDPCAAVPGAPGPPPPRAYPFAPAPGAAGSSAAESEGPGASRAAAVKAPVKKNPKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGQIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLVSAFARSRNPVASPTQPNGSDKDAAEARREFDRDSGPAALGDATHPPQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHADLRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHPAVNPAAAAAAAAAANVYSSAAAPPGAYDYCPR
Tissue specificity:Expressed in skeletal muscle, lung and testis. {ECO:0000269|PubMed:11412027}.
Induction:
Developmental stage:In the developing embryo, first expressed in the mesoderm at day 7.5. Expressed in the pharyngeal endoderm and the mesodermal cores of the pharyngeal arches at 8.5 dpc. At day 9.5, primarily expressed in the head region, specifically the mesenchyme and epithelium of the pharyngeal region and the otic vesicle epithelium. By day 12.5, expression is still observed in the latter as well as in the tongue mesenchyme, tooth buds and branching lung epithelium. {ECO:0000269|PubMed:21177346, ECO:0000269|PubMed:8853987}.
Protein families: