ESRP1_MOUSE Q3US41
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UniProt:Q3US41
Recommended name:Epithelial splicing regulatory protein 1
EC number:
Alternative names:(RNA-binding motif protein 35A) (RNA-binding protein 35A)
Cleaved into:
GeneID:207920
Gene names (primary ):Esrp1
Gene names (synonym ):Rbm35a
Gene names (ORF ):
Length:680
Mass:75549
Sequence:MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHIRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFPAPTAVIPTEAAIYQPSLLLNPRALQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLSSVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYATEDGLVHTNDQARTLPKEWVCI
Tissue specificity:Epithelial cell-specific. Epithelial-specific expression in diverse tissues and organs with particularly notable levels of expression in skin and gastrointestinal epithelia. {ECO:0000269|PubMed:19285943}.
Induction:
Developmental stage:It is broadly expressed throughout the epithelium of the otic vesicle at embryonic day 10.5 dpc, but it is absent from the surrounding mesenchyme. High expression is detected in sensory and non-sensory epithelial progenitors during cochlear and vestibular morphogenesis, although the level is weaker at later stages of inner ear development. {ECO:0000269|PubMed:29107558}.
Protein families:ESRP family