HMGN3_MOUSE   Q9DCB1


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UniProt:Q9DCB1

Recommended name:High mobility group nucleosome-binding domain-containing protein 3

EC number:

Alternative names:

Cleaved into:

GeneID:94353

Gene names  (primary ):Hmgn3

Gene names  (synonym ):

Gene names  (ORF ):

Length:99

Mass:10769

Sequence:MPKRKSPENTEGKDGTKLTKQEPTRRSARLSAKPVPPKPESKPRKTSAKKEPGTKISRGAKGKKEEKQEAGEEGTAPSANGDTKVEEAQRTESIEKEGE

Tissue specificity:Expressed in the brain, eye, prostate, thyroid, kidney, testis, glial cells and insulin-producing cells of the Langerhans pancreatic islets. In the brain, expressed in the lateral olfactory tract, anterior commissure, corpus callosum, internal capsule, fornix, stria medullans, optic tract, axon bundles, Purkinje cell layer and granular layer of the cerebellum. In retina, expressed in the nuclei of cells in the inner nuclear layer including amacrine, bipolar and horizontal neurons and in the nuclei of ganglion neurons. Detected at low levels in the liver. {ECO:0000269|PubMed:11356838, ECO:0000269|PubMed:12185205, ECO:0000269|PubMed:15082770, ECO:0000269|PubMed:18502697, ECO:0000269|PubMed:19651901, ECO:0000269|PubMed:19885867}.

Induction:

Developmental stage:Transiently expressed in the stroma and endothelium of the cornea at birth. Subsequently expressed in the corneal epithelium and the inner nuclear and ganglion cell layers of the retina. The predominant form in developing ocular tissues is isoform 2, although isoform 1 is also detectable. {ECO:0000269|PubMed:18502697}.

Protein families:HMGN family


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