Product List

Recombinant Human IL-1a (C-Fc)

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2325

SKU: PHH2348

Detail

Name	Recombinant Human IL-1a (C-Fc)
Purity	Greater than 95% as determined by reducing SDS-PAGE
Endotoxin level	<1 EU/µg as determined by LAL test.
Construction	Recombinant Human Interleukin-1 alpha is produced by our Mammalian expression system and the target gene encoding Ser113-Ala271 is expressed with a human IgG1 Fc tag at the C-terminus.
Accession #	P01583
Host	Human Cells
Species	Human
Predicted Molecular Mass	44.9 KDa
Buffer	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Form	Lyophilized
Shipping	The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Stability&Storage	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Alternative Names

Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1

Background

Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.

Note

For Research Use Only , Not for Diagnostic Use.