Recombinant Human/Murine/Rat BDNF

Recombinant Human/Murine/Rat BDNF

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2325 SKU: PEV0147 Category: Cytokines Tags: , , ,

Datasheet

Name

Recombinant Human/Murine/Rat BDNF

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<0.01 EU/µg as determined by LAL test.

Construction

Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.

Accession #

P23560

Host

E.coli

Species

Human/Mouse/Rat

Predicted Molecular Mass

13 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Brain-Derived Neurotrophic Factor; BDNF; Abrineurin

 

Background

Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinsons and Alzheimers disease.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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