Alternative Names
Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B
Background
Fibroblast growth factor 8 (FGF/xad8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen-/xaddependent growth of mouse mammary carcinoma cells. Mouse FGF/xad8b shares 100% aa identity with human FGF/xad8b. FGF/xad8 is widely expressed during embryogenesis, and mediates epithelial/xad-mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
Note
For Research Use Only , Not for Diagnostic Use.
