Recombinant Human Fibronectin
Recombinant Human Fibronectin
Size1:10μg price1:$40
Size2:50μg price2:$90
SKU: PCH2511
Detail
Name

Recombinant Human Fibronectin

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

≤10 EU/mg

Construction

Recombinant Human Fibronectin is produced by our Mammalian cell expression system and the target gene encoding Pro1270-Ser1546&Ala1721-Thr2016 is expressed.

Accession #

P02751

Host

Human Cells

Species

Human

Predicted Molecular Mass

62.6 kDa

Buffer

Lyophilized From PBS,5% mannitol and 0.01% Tween 80, pH7.4

Form

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

FN; Cold-insoluble globulin; CIG; FN; Fibronectin 1

 

Background

Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a heparin binding domain II, which co-locates the cell and the virus vector on NovoNectin. This process enhances the density of both cells and vectors, and facilitates the gene transduction in the result.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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