Oct-4 Rabbit Monoclonal Antibody

Oct-4 Rabbit Monoclonal Antibody

Size1:50μL Price1:$138
Size2:100μL Price2:$240
Size3:200μL Price3:$380
Application:WB,IHC,IF,IP,ELISA
Reactivity:Human,Mouse
Conjugate:Unconjugated
Gene Name:POU5F1 SKU: AMRe21385 Category: Recombinant Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

Oct-4 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC,IF,IP,ELISA

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG,Kappa

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein

Purification

Protein A

 

Immunogen

Gene Name

POU5F1

Alternative Names

POU5F1;OCT3;OCT4;OTF3;POU domain; class 5, transcription factor 1;Octamer-binding protein 3;Oct-3;Octamer-binding protein 4;Oct-4;Octamer-binding transcription factor 3;OTF-3

Gene ID

5460

SwissProt ID

Q01860

 

Application

Dilution Ratio

IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

Molecular Weight

Calculated MW:39kD;Observed MW:45kD

 

Background

Cell localization:Nucleus.This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation withThe Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One ofThe AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],

 

Research Area

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