Summary
Performance
Immunogen
Application
Background
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015]
Research Area
Cell Biology; Cell Cycle; Cell Cycle Inhibitors; Cardiovascular; Angiogenesis; Adhesion / ECM; Extracellular Matrix; Signal Transduction; Protein Phosphorylation; Tyrosine Kinases; Receptor Tyrosine Kinases; Cytoskeleton / ECM; Extracellular Matrix; Structures; Bone; Stem Cells; Lineage Markers; Endoderm; Mesenchymal Stem Cells; Osteogenesis; Cancer; Developmental Biology; Lineage specification
