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Transferrin

Transferrin (TRF) is an important glycoprotein in human plasma, mainly synthesized in the liver. It is composed of 679 amino acid residues, with glycose accounting for about 6%. It has two highly homologous domains, the N - terminal and C - terminal. Each domain has a Fe³⁺ binding site and can reversibly bind two Fe³⁺. Transferrin can be divided into common transferrin, iron - saturated transferrin, etc. according to the iron - containing number, and can be divided into common - type transferrin and iso - type transferrin according to the configuration. Its main function is to act as a carrier for iron transport, transporting iron ions from absorption and storage sites to red blood cells and other iron - requiring cells, participating in the regulation of iron metabolism and balance, and also playing a role in respiration, cell proliferation, immune system regulation, and antibacterial and bactericidal aspects.

Product List

Validation Data

GMP Recombinant Human Transferrin (HOLO) (Catalog: PCH90044)

             Transferrin (HOLO) SDS-PAGE image

                        Bioactivity image: The ED50 for this effect is 0.5-2 μg/mL.

GMP Recombinant Human Transferrin(APO) (Catalog: PCH90046)

                        Bioactivity image: The ED50 for this effect is ≤5 μg/mL.