SMYD2_MOUSE Q8R5A0
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UniProt:Q8R5A0
Recommended name:N-lysine methyltransferase SMYD2
EC number:EC 2.1.1.-
Alternative names:(Histone methyltransferase SMYD2) (SET and MYND domain-containing protein 2)
Cleaved into:
GeneID:226830
Gene names (primary ):Smyd2
Gene names (synonym ):
Gene names (ORF ):
Length:433
Mass:49567
Sequence:MRAEARGGLERFCSAGKGRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLECSSMVVLGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVREFESHLDKLDNEKKDLIQSDIAALHQFYSKYLEFPDHSSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGDEVFTSYIDLLYPTEDRNDRLRDSYFFTCECRECTTKDKDKAKVEVRKLSSPPQAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALKYGQKIIKPYSKHYPVYSLNVASMWLKLGRLYMGLENKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH
Tissue specificity:Highly expressed in heart, skeletal muscle and brain tissue. During cardiac development, it is differentially expressed with highest expression in the neonatal heart while very low expression is detected at E12.5 and adult. Specifically expressed in cardiomyocytes (at protein level). {ECO:0000269|PubMed:20305823}.
Induction:
Developmental stage:
Protein families:Class V-like SAM-binding methyltransferase superfamily