Summary
| Production Name | HBP1 (phospho Ser402) Rabbit Polyclonal Antibody |
| Description | Rabbit polyclonal Antibody |
| Host | Rabbit |
| Application | WB,IHC,ICC/IF,ELISA |
| Reactivity | Human,Rat,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Phosphorylated |
| Isotype | IgG |
| Clonality | Polyclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Purification | Affinity purification |
Immunogen
| Gene Name | HBP1 |
| Alternative Names | HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1 |
| Gene ID | 26959 |
| SwissProt ID | O60381 |
Application
| Dilution Ratio | WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:10000 |
| Molecular Weight | 58kDa |
Background
function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,
Research Area