Name | Recombinant Human XPNPEP3 (N, C-6His) |
Purity | Greater than 95% as determined by reducing SDS-PAGE |
Endotoxin level | <1 EU/µg as determined by LAL test. |
Construction | Recombinant Human Probable Xaa-Pro Aminopeptidase 3 is produced by our E.coli expression system and the target gene encoding Met1-Ser507 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus. |
Accession # | Q9NQH7 |
Host | E.coli |
Species | Human |
Predicted Molecular Mass | 60.2 KDa |
Buffer | Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 1mM DTT, pH 7.3. |
Form | Liquid |
Shipping | The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
Stability&Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Alternative Names
Probable Xaa-Pro Aminopeptidase 3; X-Pro Aminopeptidase 3; Aminopeptidase P3; APP3; XPNPEP3
Background
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
Note
For Research Use Only , Not for Diagnostic Use.