Alternative Names
Group XVI Phospholipase A1/A2; Adipose-Specific Phospholipase A2; AdPLA; H-Rev 107 Protein Homolog; HRAS-Like Suppressor 1; HRAS-Like Suppressor 3; HRSL3; HREV107-1; HREV107-3; Renal Carcinoma Antigen NY-REN-65; PLA2G16; HRASLS3; HREV107
Background
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.
Note
For Research Use Only , Not for Diagnostic Use.
