Recombinant Human PADI4 (N-6His)
Recombinant Human PADI4 (N-6His)
Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2350
SKU: PEH1260
Detail
Name

Recombinant Human PADI4 (N-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Protein-Arginine Deiminase Type-4 is produced by our E.coli expression system and the target gene encoding Met1-Pro663 is expressed with a 6His tag at the N-terminus.

Accession #

AAH25718.1

Host

E.coli

Species

Human

Predicted Molecular Mass

76.2 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 500mM NaCl, pH 7.5.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase type IV; PADI4; PADI5; PDI5

 

Background

Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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