Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody

Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200 SKU: AMRe03054 Category: Rabbit Monoclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,ICC/IF

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

F11R

Alternative Names

F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321

Gene ID

50848

SwissProt ID

Q9Y624

 

Application

Dilution Ratio

WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Molecular Weight

Calculated MW: 33 kDa; Observed MW: 33 kDa

 

Background

Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

 

Research Area

Cardiovascular

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