MLK3 Rabbit Monoclonal Antibody-Rabbit Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

MLK3 Rabbit Monoclonal Antibody

Summary

Production Name	MLK3 Rabbit Monoclonal Antibody
Description	Recombinant Rabbit Monoclonal antibody
Host	Rabbit
Application	WB
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification	Affinity Purified

Immunogen

Gene Name	MAP3K11
Alternative Names	MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
Gene ID	4296
SwissProt ID	Q16584

Application

Dilution Ratio	WB: 1/500-1/1000
Molecular Weight	Calculated MW: 93 kDa; Observed MW: 93 kDa

Background

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Research Area

Signal Transduction