Recombinant Human FKBP4 (C-6His)
Recombinant Human FKBP4 (C-6His)
Size1:10μg price1:$52
Size2:50μg price2:$108
Size3:500μg price3:$1240
SKU: PEH0671
Detail
Name

Recombinant Human FKBP4 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.

Accession #

Q02790

Host

E.coli

Species

Human

Predicted Molecular Mass

52.8 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Peptidyl-prolyl cis-trans isomerase FKBP4; 51kDa FK506-binding protein; 51kDa FK506-binding protein; 59kDa immunophilin; FK506-binding protein 4; FKBP59; HSP-binding immunophilin; immunophilin FKBP52; Rotamase; FKBP4

 

Background

FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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