Summary
| Production Name | Doublecortin Rabbit Monoclonal Antibody |
| Description | Recombinant Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB |
| Reactivity | Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification | Affinity Purified |
Immunogen
| Gene Name | DCX |
| Alternative Names | DCX; DBCN; LISX; Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X |
| Gene ID | 1641 |
| SwissProt ID | O43602 |
Application
| Dilution Ratio | WB: 1/500-1/1000 |
| Molecular Weight | Calculated MW: 41 kDa; Observed MW: 41 kDa |
Background
Mutations in Doublecortin cause Lissencephaly (smooth brain), a neuronal migration disorder characterized by epilepsy and mental retardation. Doublecortin is a microtubule associated protein that stabilizes and bundles microtubules. A conserved doublecortin domain mediates the interaction with microtubules, and interestingly most missense mutations cluster in this domain.
Research Area
Cell Biology
