PLSCR3 Rabbit Monoclonal Antibody

PLSCR3 Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200
SKU: AMRe02453 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

PLSCR3 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

PLSCR3

Alternative Names

Phospholipid scramblase 3; PL scramblase 3

Gene ID

57048

SwissProt ID

Q9NRY6

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 32 kDa; Observed MW: 32 kDa

 

Background

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

 

Research Area

Cardiovascular