| Name | Recombinant Human DHS (C-6His) |
| Purity | Greater than 95% as determined by reducing SDS-PAGE |
| Endotoxin level | <1 EU/µg as determined by LAL test. |
| Construction | Recombinant Human Deoxyhypusine Synthase is produced by our E.coli expression system and the target gene encoding Met1-Asp369 is expressed with a 6His tag at the C-terminus. |
| Accession # | P49366 |
| Host | E.coli |
| Species | Human |
| Predicted Molecular Mass | 42.04 KDa |
| Buffer | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, pH 8.0. |
| Form | Liquid |
| Shipping | The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| Stability&Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Alternative Names
Deoxyhypusine Synthase; DHS; DHPS; DS
Background
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Note
For Research Use Only , Not for Diagnostic Use.