Laminin alpha 5 Rabbit Polyclonal Antibody

Laminin alpha 5 Rabbit Polyclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: APRab00405 Category: Polyclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

Laminin alpha 5 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC,ELISA

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

LAMA5

Alternative Names

Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

Gene ID

3911

SwissProt ID

O15230

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Molecular Weight

Calculated MW: 400 kDa; Observed MW: 400 kDa

 

Background

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

 

Research Area

Signal Transduction