Growth Hormone Receptor Rabbit Polyclonal Antibody

Growth Hormone Receptor Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200 SKU: APRab00223 Category: Polyclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Growth Hormone Receptor Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

GHR

Alternative Names

GHR; Growth hormone receptor; GH receptor; Somatotropin receptor

Gene ID

2690

SwissProt ID

P10912

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 72 kDa; Observed MW: 140 kDa

 

Background

Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

 

Research Area

Signal Transduction

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