Summary
| Production Name | Cullin 3 Rabbit Polyclonal Antibody |
| Description | Primary antibody |
| Host | Rabbit |
| Application | WB |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Polyclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity Chromatography |
Immunogen
| Gene Name | CUL3 |
| Alternative Names | CUL3; KIAA0617; Cullin-3; CUL-3 |
| Gene ID | 8452 |
| SwissProt ID | Q13618 |
Application
| Dilution Ratio | WB: 1/500-1/1000 |
| Molecular Weight | Calculated MW: 89 kDa; Observed MW: 89 kDa |
Background
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Research Area
Cell Biology
