Phospho-IGF1 Receptor (Tyr1165/Tyr1166) Rabbit Polyclonal Antibody

Phospho-IGF1 Receptor (Tyr1165/Tyr1166) Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: APRab00790 Category: Polyclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

Phospho-IGF1 Receptor (Tyr1165/Tyr1166) Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,ELISA

Reactivity

Human,Mouse,Rat,Monkey

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

IGF1R

Alternative Names

IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Gene ID

3480

SwissProt ID

P08069

 

Application

Dilution Ratio

WB: 1/500-1/1000 ELISA: 1/10000

Molecular Weight

Calculated MW: 155 kDa; Observed MW: 155 kDa

 

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

 

Research Area

Signal Transduction