Alternative Names
Interleukin-18 receptor 1; IL18R1; CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; Interleukin-18 receptor alpha; IL-18R-alpha; CD218a; IL1RRP
Background
The interleukin 18 receptor 1 (IL18R1) belongs to interleukin 1 receptor family. IL18R1 is of particular interest since the receptor is critical for experimental neuroinflammation. Reaserches show that the increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. IL18R1 has been shown to mediate EAE through regulation of both IL-18-dependent and –independent pathways.
Note
For Research Use Only , Not for Diagnostic Use.