Recombinant Human IRF5 (C-6His)

Recombinant Human IRF5 (C-6His)

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2325 SKU: PEH0966 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Human IRF5 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.

Accession #

Q13568

Host

E.coli

Species

Human

Predicted Molecular Mass

57.1 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 30% Glycerol, 1mM DTT, pH 8.0.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Interferon Regulatory Factor 5; IRF-5; IRF5

 

Background

Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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