Recombinant Human HMGB3 (C-6His)

Recombinant Human HMGB3 (C-6His)

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890 SKU: PHH0802 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Human HMGB3 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human High Mobility Group Protein B3 is produced by our Mammalian expression system and the target gene encoding Met1-Glu200 is expressed with a 6His tag at the C-terminus.

Accession #

O15347

Host

Human Cells

Species

Human

Predicted Molecular Mass

24 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 8% Trehalose, 2% Mannitol, 0.05% Tween80, 2mM EDTA, pH7.0.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

High Mobility Group Protein B3; High Mobility Group Protein 2a; HMG-2a; High Mobility Group Protein 4; HMG-4; HMGB3; HMG2A; HMG4

 

Background

High Mobility Group Protein B3 (HMGB3) belongs to the HMGB family. Members of the HMG box subfamily are thought to be have an important role in DNA replication, nucleosome assembly and transcription. HMGB3 binds preferentiallly single-stranded DNA and unwinds double stranded DNA. HMGB3 consists of 200 amino acids and is localized to the cell nucleus. It contains two HMG box DNA-binding domain. HMGB3 binds preferentially single-stranded DNA and unwinds double stranded DNA.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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