Recombinant Mouse CCL9

Recombinant Mouse CCL9

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890
SKU: PEM0275 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Mouse CCL9

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Mouse C-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Gln22-Gln122 is expressed.

Accession #

P51670

Host

E.coli

Species

Mouse

Predicted Molecular Mass

11.6 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM His-HCl, 8% Sucrose, 0.05% Tween80, pH5.5.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

C-C motif chemokine 9; CCF18; Macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; Small-inducible cytokine A9; Scya10; Scya9 and CCL9

 

Background

C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.

 

Note

For Research Use Only , Not for Diagnostic Use.