Alternative Names
Killer cell lectin-like receptor subfamily F member 1; Lectin-like receptor F1; KLRF1; Activating coreceptor NKp80; C-type lectin domain family 5 member C; CLEC5C
Background
Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its function involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
Note
For Research Use Only , Not for Diagnostic Use.