Recombinant Human MKI67 (N-GST)

Recombinant Human MKI67 (N-GST)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1980
SKU: PEH2353 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human MKI67 (N-GST)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Proliferation Marker Protein Ki-67 is produced by our E.coli expression system and the target gene encoding Met1-Pro120 is expressed with a GST tag at the N-terminus.

Accession #

P46013

Host

E.coli

Species

Human

Predicted Molecular Mass

40.1 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH 8.0.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Antigen Ki67; antigen KI-67; Ki67; Ki-67; KIA; MIB-; MIB-1; MKI67; PPP1R105

 

Background

MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis.

 

Note

For Research Use Only , Not for Diagnostic Use.