NEIL3 Rabbit Polyclonal Antibody($99/20μL)

NEIL3 Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$128
Size3:100μL Price2:$230
Size4:200μL Price3:$380
Application:WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:NEIL3 SKU: APRab14547 Category: Polyclonal Antibody Tags: , , , , , , , ,

Datasheet

Summary

Production Name

NEIL3 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

NEIL3

Alternative Names

NEIL3; Endonuclease 8-like 3; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3

Gene ID

55247

SwissProt ID

Q8TAT5

 

Application

Dilution Ratio

WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:40000, IF-P/IF-F/ICC/IF 1:50-200

Molecular Weight

35kDa

 

Background

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008],function:Reports about DNA glycosylase activity are contradictory. The protein lacks a proline residue at the N-terminus that is the active site residue found in the other members of the FPG family.,similarity:Belongs to the FPG family.,similarity:Contains 1 FPG-type zinc finger.,similarity:Contains 1 RanBP2-type zinc finger.,tissue specificity:Detected in thymus and testis.,

 

Research Area

Base excision repair;

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