Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody

Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody

Size1:50μL Price1:$138
Size2:100μL Price2:$240
Size3:200μL Price3:$380
Application:WB,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MYC SKU: AMRe05880 Category: Rabbit Monoclonal Antibody Tags: , , , , , , , ,

Datasheet

Summary

Production Name

Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB,ICC/IF,FC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phospho Antibody

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

MYC

Alternative Names

MRTL; MYC; Myc proto-oncogene protein; c-myc;

Gene ID

4609

SwissProt ID

P01106

 

Application

Dilution Ratio

WB 1:1000, ICC/IF 1:100-1:200, FCM 1:200-1:1000

Molecular Weight

49kDa

 

Background

Myc a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors. Seems to activate the transcription of growth-related genes. Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).

 

Research Area

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