Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody

Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody

Size1:50μl Price1:$138
Size2:100μl Price2:$240
Size3:500μl Price3:$980 SKU: AMRe05880 Category: Rabbit Monoclonal Antibody Tags: , ,

Datasheet

Summary

Production Name

Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Phospho Antibody

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

MYC

Alternative Names

MRTL; MYC; Myc proto-oncogene protein; c-myc;

Gene ID

4609

SwissProt ID

P01106

 

Application

Dilution Ratio

WB 1:500-1:2000

Molecular Weight

49kDa

 

Background

Myc a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors. Seems to activate the transcription of growth-related genes. Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).

 

Research Area

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