KMT6 Rabbit Monoclonal antibody

KMT6 Rabbit Monoclonal antibody

Size1:50μL Price1:$158 $99
Size2:100μL Price2:$288 $180
Application:WB,ICC/IF
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:EZH2 SKU: AMRe02196 Category: Rabbit Monoclonal Antibody Tags: , , , , , , , ,

Datasheet

Summary

Production Name

KMT6 Rabbit Monoclonal antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,ICC/IF

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

EZH2

Alternative Names

WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2

Gene ID

2146

SwissProt ID

Q15910

 

Application

Dilution Ratio

WB: 1:500-1:1000 IF: 1:50-1:200

Molecular Weight

Calculated MW: 85 kDa; Observed MW: 98 kDa

 

Background

Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

 

Research Area

Epigenetics and Nuclear Signaling

Related products