KMT6 Rabbit Monoclonal Antibody

KMT6 Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200
SKU: AMRe02196 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

KMT6 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

EZH2

Alternative Names

WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2

Gene ID

2146

SwissProt ID

Q15910

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 85 kDa; Observed MW: 98 kDa

 

Background

Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

 

Research Area

Epigenetics and Nuclear Signaling