XAF1_HUMAN Q6GPH4
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UniProt:Q6GPH4
Recommended name：XIAP-associated factor 1
EC number：
Alternative names：(BIRC4-binding protein)
Cleaved into：
GeneID：54739
Gene names (primary )：XAF1
Gene names (synonym )：BIRC4BP XIAPAF1
Gene names (ORF )：
Length：301
Mass：34626
Sequence：MEGDFSVCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCTMCQQSMQKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQHRDVCRSEQAQLGKGERISAPEREIYCHYCNQMIPENKYFHHMGKCCPDSEFKKHFPVGNPEILPSSLPSQAAENQTSTMEKDVRPKTRSINRFPLHSESSSKKAPRSKNKTLDPLLMSEPKPRTSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS
Tissue specificity：Widely expressed. Expression is frequently down-regulated in cancer cell lines. Isoform 5 is widely expressed. Expressed in placenta (at protein level). {ECO:0000269|PubMed:11175744, ECO:0000269|PubMed:16343440, ECO:0000269|PubMed:17329253, ECO:0000269|PubMed:17570219}.
Induction：Up-regulated by IFNB1/IFN-beta in cell lines sensitive to the proapoptotic effects of IFNB1 but not in apoptosis-resistant cells. Up-regulated by TNF in trophoblast cells. {ECO:0000269|PubMed:12029096, ECO:0000269|PubMed:17329253}.
Developmental stage：Selectively expressed in third trimester placenta. {ECO:0000269|PubMed:17329253}.
Protein families：