UHMK1_HUMAN   Q8TAS1


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UniProt:Q8TAS1

Recommended name:Serine/threonine-protein kinase Kist

EC number:EC:2.7.11.1

Alternative names:(Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1)

Cleaved into:

GeneID:127933

Gene names  (primary ):UHMK1

Gene names  (synonym ):KIS KIST

Gene names  (ORF ):

Length:419

Mass:46546

Sequence:MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGNPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSELLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGLSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMKLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALCSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSLLVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL

Tissue specificity:Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:12093740}.

Induction:

Developmental stage:Regulated in a cell-cycle dependent manner, with lowest levels during S phase and highest at G1 phase (at protein level). {ECO:0000269|PubMed:23419774}.

Protein families:Protein kinase superfamily, Ser/Thr protein kinase family