UHMK1_HUMAN Q8TAS1
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UniProt:Q8TAS1
Recommended name:Serine/threonine-protein kinase Kist
EC number:EC:2.7.11.1
Alternative names:(Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1)
Cleaved into:
GeneID:127933
Gene names (primary ):UHMK1
Gene names (synonym ):KIS KIST
Gene names (ORF ):
Length:419
Mass:46546
Sequence:MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGNPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSELLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGLSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMKLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALCSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSLLVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL
Tissue specificity:Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:12093740}.
Induction:
Developmental stage:Regulated in a cell-cycle dependent manner, with lowest levels during S phase and highest at G1 phase (at protein level). {ECO:0000269|PubMed:23419774}.
Protein families:Protein kinase superfamily, Ser/Thr protein kinase family