MCIN_HUMAN D6RGH6
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UniProt:D6RGH6
Recommended name:Multicilin
EC number:
Alternative names:(Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas)
Cleaved into:
GeneID:345643
Gene names (primary ):MCIDAS
Gene names (synonym ):IDAS MCI MCIN
Gene names (ORF ):
Length:385
Mass:41720
Sequence:MQACGGGAAGRRAFDSICPNRMLALPGRALLCKPGKPERKFAPPRKFFPGCTGGSPVSVYEDPPDAEPTALPALTTIDLQDLADCSSLLGSDAPPGGDLAASQNHSHQTEADFNLQDFRDTVDDLISDSSSMMSPTLASGDFPFSPCDISPFGPCLSPPLDPRALQSPPLRPPDVPPPEQYWKEVADQNQRALGDALVENNQLHVTLTQKQEEIASLKERNVQLKELASRTRHLASVLDKLMITQSRDCGAAAEPFLLKAKAKRSLEELVSAAGQDCAEVDAILREISERCDEALQSRDPKRPRLLPEPANTDTRPGNLHGAFRGLRTDCSRSALNLSHSELEEGGSFSTRIRSHSTIRTLAFPQGNAFTIRTANGGYKFRWVPS
Tissue specificity:
Induction:
Developmental stage:Probable target of the anaphase promoting complex/cyclosome (APC/C) which regulates its level in the cell during the mitotic cell cycle. Highly expressed during interphase and early mitosis. Expression decreases during anaphase to become undetectable during telophase and cytokinesis. Expressed in cells destined for multiciliated cell differentiation, its expression is very weak in fully differentiated ciliated respiratory cells (PubMed:25048963). {ECO:0000269|PubMed:21543332, ECO:0000269|PubMed:25048963}.
Protein families:Geminin family