MCIN_HUMAN   D6RGH6


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UniProt:D6RGH6

Recommended name:Multicilin

EC number:

Alternative names:(Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas)

Cleaved into:

GeneID:345643

Gene names  (primary ):MCIDAS

Gene names  (synonym ):IDAS MCI MCIN

Gene names  (ORF ):

Length:385

Mass:41720

Sequence:MQACGGGAAGRRAFDSICPNRMLALPGRALLCKPGKPERKFAPPRKFFPGCTGGSPVSVYEDPPDAEPTALPALTTIDLQDLADCSSLLGSDAPPGGDLAASQNHSHQTEADFNLQDFRDTVDDLISDSSSMMSPTLASGDFPFSPCDISPFGPCLSPPLDPRALQSPPLRPPDVPPPEQYWKEVADQNQRALGDALVENNQLHVTLTQKQEEIASLKERNVQLKELASRTRHLASVLDKLMITQSRDCGAAAEPFLLKAKAKRSLEELVSAAGQDCAEVDAILREISERCDEALQSRDPKRPRLLPEPANTDTRPGNLHGAFRGLRTDCSRSALNLSHSELEEGGSFSTRIRSHSTIRTLAFPQGNAFTIRTANGGYKFRWVPS

Tissue specificity:

Induction:

Developmental stage:Probable target of the anaphase promoting complex/cyclosome (APC/C) which regulates its level in the cell during the mitotic cell cycle. Highly expressed during interphase and early mitosis. Expression decreases during anaphase to become undetectable during telophase and cytokinesis. Expressed in cells destined for multiciliated cell differentiation, its expression is very weak in fully differentiated ciliated respiratory cells (PubMed:25048963). {ECO:0000269|PubMed:21543332, ECO:0000269|PubMed:25048963}.

Protein families:Geminin family