SETD3_HUMAN   Q86TU7


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UniProt:Q86TU7

Recommended name:Actin-histidine N-methyltransferase

EC number:EC:2.1.1.85

Alternative names:(SET domain-containing protein 3) (hSETD3)

Cleaved into:

GeneID:84193

Gene names  (primary ):SETD3

Gene names  (synonym ):C14orf154

Gene names  (ORF ):

Length:594

Mass:67257

Sequence:MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKATENGLVNGENSIPNGTRSENESLNQESKRAVEDAKGSSSDSTAGVKE

Tissue specificity:

Induction:

Developmental stage:Protein levels peak in S phase and are lowest during M phase (at protein level). {ECO:0000269|PubMed:28442573}.

Protein families:Class V-like SAM-binding methyltransferase superfamily, SETD3 actin-histidine methyltransferase family