SETD3_HUMAN Q86TU7
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UniProt:Q86TU7
Recommended name:Actin-histidine N-methyltransferase
EC number:EC:2.1.1.85
Alternative names:(SET domain-containing protein 3) (hSETD3)
Cleaved into:
GeneID:84193
Gene names (primary ):SETD3
Gene names (synonym ):C14orf154
Gene names (ORF ):
Length:594
Mass:67257
Sequence:MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKATENGLVNGENSIPNGTRSENESLNQESKRAVEDAKGSSSDSTAGVKE
Tissue specificity:
Induction:
Developmental stage:Protein levels peak in S phase and are lowest during M phase (at protein level). {ECO:0000269|PubMed:28442573}.
Protein families:Class V-like SAM-binding methyltransferase superfamily, SETD3 actin-histidine methyltransferase family