S10AC_HUMAN P80511
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UniProt:P80511
Recommended name:Protein S100-A12
EC number:
Alternative names:(CGRP) (Calcium-binding protein in amniotic fluid 1) (CAAF1) (Calgranulin-C) (CAGC) (Extracellular newly identified RAGE-binding protein) (EN-RAGE) (Migration inhibitory factor-related protein 6) (MRP-6) (p6) (Neutrophil S100 protein) (S100 calcium-binding protein A12)
Cleaved into:Calcitermin
GeneID:6283
Gene names (primary ):S100A12
Gene names (synonym ):
Gene names (ORF ):
Length:92
Mass:10575
Sequence:MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE
Tissue specificity:Predominantly expressed by neutrophils, monocytes and activated macrophages. Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate. Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease.
Induction:
Developmental stage:
Protein families:S-100 family