AL7A1_HUMAN P49419
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UniProt:P49419
Recommended name:Alpha-aminoadipic semialdehyde dehydrogenase
EC number:EC:1.2.1.31
Alternative names:(Alpha-AASA dehydrogenase) (Aldehyde dehydrogenase family 7 member A1) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)
Cleaved into:
GeneID:501
Gene names (primary ):ALDH7A1
Gene names (synonym ):ATQ1
Gene names (ORF ):
Length:539
Mass:58487
Sequence:MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
Tissue specificity:Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. {ECO:0000269|PubMed:8088832, ECO:0000269|PubMed:9417906}.
Induction:
Developmental stage:
Protein families:Aldehyde dehydrogenase family