AL7A1_HUMAN   P49419


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UniProt:P49419

Recommended name:Alpha-aminoadipic semialdehyde dehydrogenase

EC number:EC:1.2.1.31

Alternative names:(Alpha-AASA dehydrogenase) (Aldehyde dehydrogenase family 7 member A1) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)

Cleaved into:

GeneID:501

Gene names  (primary ):ALDH7A1

Gene names  (synonym ):ATQ1

Gene names  (ORF ):

Length:539

Mass:58487

Sequence:MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ

Tissue specificity:Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. {ECO:0000269|PubMed:8088832, ECO:0000269|PubMed:9417906}.

Induction:

Developmental stage:

Protein families:Aldehyde dehydrogenase family