PPM1D_HUMAN O15297
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UniProt:O15297
Recommended name：Protein phosphatase 1D
EC number：EC:3.1.3.16
Alternative names：(Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)
Cleaved into：
GeneID：8493
Gene names (primary )：PPM1D
Gene names (synonym )：WIP1
Gene names (ORF )：
Length：605
Mass：66675
Sequence：MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAKALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC
Tissue specificity：Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts. {ECO:0000269|PubMed:28343630}.
Induction：By p53/TP53. {ECO:0000269|PubMed:15870257, ECO:0000269|PubMed:9177166}.
Developmental stage：
Protein families：PP2C family