X3CL1_HUMAN P78423
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UniProt:P78423
Recommended name：Fractalkine
EC number：
Alternative names：(C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1)
Cleaved into：Processed fractalkine
GeneID：6376
Gene names (primary )：CX3CL1
Gene names (synonym )：FKN NTT SCYD1
Gene names (ORF )：A-152E5.2
Length：397
Mass：42203
Sequence：MAPISLSWLLRLATFCHLTVLLAGQHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAAALTRNGGTFEKQIGEVKPRTTPAAGGMDESVVLEPEATGESSSLEPTPSSQEAQRALGTSPELPTGVTGSSGTRLPPTPKAQDGGPVGTELFRVPPVSTAATWQSSAPHQPGPSLWAEAKTSEAPSTQDPSTQASTASSPAPEENAPSEGQRVWGQGQSPRPENSLEREEMGPVPAHTDAFQDWGPGSMAHVSVVPVSSEGTPSREPVASGSWTPKAEEPIHATMDPQRLGVLITPVPDAQAATRRQAVGLLAFLGLLFCLGVAMFTYQSLQGCPRKMAGEMAEGLRYIPRSCGSNSYVLVPV
Tissue specificity：Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. Most abundant in the brain and heart. {ECO:0000269|PubMed:23765988, ECO:0000269|PubMed:9024663, ECO:0000269|PubMed:9177350}.
Induction：By TNF and IL1/interleukin-1 in pulmonary endothelial cells and umbilical vein endothelial cells. {ECO:0000269|PubMed:9024663}.
Developmental stage：
Protein families：Intercrine delta family