CDN1B_HUMAN P46527
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UniProt:P46527
Recommended name:Cyclin-dependent kinase inhibitor 1B
EC number:
Alternative names:(Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Cleaved into:
GeneID:1027
Gene names (primary ):CDKN1B
Gene names (synonym ):KIP1
Gene names (ORF ):
Length:198
Mass:22073
Sequence:MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
Tissue specificity:Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.
Induction:Maximal levels in quiescence cells and early G(1). Levels decrease after mitogen stimulation as cells progress toward S-phase. {ECO:0000269|PubMed:17254966}.
Developmental stage:
Protein families:CDI family