NOX4_HUMAN Q9NPH5
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UniProt:Q9NPH5
Recommended name：NADPH oxidase 4
EC number：EC:1.6.3.-
Alternative names：(Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) (Renal NAD(P)H-oxidase)
Cleaved into：
GeneID：50507
Gene names (primary )：NOX4
Gene names (synonym )：RENOX
Gene names (ORF )：
Length：578
Mass：66932
Sequence：MAVSWRSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGLTGVCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYRYIRSNKPVTIISVMSHPSDVMEIRMVKENFKARPGQYITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRFEYNKESFS
Tissue specificity：Expressed by distal tubular cells in kidney cortex and in endothelial cells (at protein level). Widely expressed. Strongly expressed in kidney and to a lower extent in heart, adipocytes, hepatoma, endothelial cells, skeletal muscle, brain, several brain tumor cell lines and airway epithelial cells. {ECO:0000269|PubMed:11032835, ECO:0000269|PubMed:11376945, ECO:0000269|PubMed:15210697, ECO:0000269|PubMed:16324151}.
Induction：By 7-ketocholesterol (at protein level). {ECO:0000269|PubMed:15572675}.
Developmental stage：Expressed in fetal kidney and fetal liver. {ECO:0000269|PubMed:10869423, ECO:0000269|PubMed:11032835, ECO:0000269|PubMed:11376945}.
Protein families：