MUS81_HUMAN Q96NY9
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UniProt:Q96NY9
Recommended name：Crossover junction endonuclease MUS81
EC number：EC:3.1.22.-
Alternative names：
Cleaved into：
GeneID：80198
Gene names (primary )：MUS81
Gene names (synonym )：
Gene names (ORF )：
Length：551
Mass：61173
Sequence：MAAPVRLGRKRPLPACPNPLFVRWLTEWRDEATRSRRRTRFVFQKALRSLRRYPLPLRSGKEAKILQHFGDGLCRMLDERLQRHRTSGGDHAPDSPSGENSPAPQGRLAEVQDSSMPVPAQPKAGGSGSYWPARHSGARVILLVLYREHLNPNGHHFLTKEELLQRCAQKSPRVAPGSARPWPALRSLLHRNLVLRTHQPARYSLTPEGLELAQKLAESEGLSLLNVGIGPKEPPGEETAVPGAASAELASEAGVQQQPLELRPGEYRVLLCVDIGETRGGGHRPELLRELQRLHVTHTVRKLHVGDFVWVAQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLERRVYLVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTRGLQRLYQGHTLRSRPWGTPGNPESGAMTSPNPLCSLLTFSDFNAGAIKNKAQSVREVFARQLMQVRGVSGEKAAALVDRYSTPASLLAAYDACATPKEQETLLSTIKCGRLQRNLGPALSRTLSQLYCSYGPLT
Tissue specificity：Widely expressed.
Induction：Up-regulated in cells treated with agents that damage DNA or block replication. This up-regulation seems to be independent of transcription. {ECO:0000269|PubMed:11741546}.
Developmental stage：Expressed in S phase and G2 phase. {ECO:0000269|PubMed:14638871}.
Protein families：XPF family