PRKX_HUMAN P51817
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UniProt:P51817
Recommended name：cAMP-dependent protein kinase catalytic subunit PRKX
EC number：EC:2.7.11.1
Alternative names：(PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (Protein kinase PKX1)
Cleaved into：
GeneID：5613
Gene names (primary )：PRKX
Gene names (synonym )：PKX1
Gene names (ORF )：
Length：358
Mass：40896
Sequence：MEAPGLAQAAAAESDSRKVAEETPDGAPALCPSPEALSPEPPVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPENDWDTAAPVPQKDLEIFKNF
Tissue specificity：Widely expressed (at protein level). Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982. {ECO:0000269|PubMed:15879576, ECO:0000269|PubMed:16236808, ECO:0000269|PubMed:7633447, ECO:0000269|PubMed:9860982}.
Induction：Up-regulated by phorbol 12-myristate 13-acetate (PMA). {ECO:0000269|PubMed:16491121, ECO:0000269|PubMed:9860982}.
Developmental stage：Expression is developmentally regulated being high and specific in a wide range of developing tissues including liver, kidney, brain and pancreas (at protein level). {ECO:0000269|PubMed:12082174, ECO:0000269|PubMed:15879576, ECO:0000269|PubMed:16236808}.
Protein families：Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily